Ideal experiments haven't been executed on the connection of age to the results of codeine in the pediatric populace. It should not be used in young children young than 12 a long time of age. Security and efficacy have not been proven.
S obzirom na to da je rizik od pojave fenomena obustave/rebound fenomena veći ukoliko se terapija naglo prekine, preporučuje se postepeno smanjivanje doze.
Simptomi obustave se javljaju kada se benzodiazepini primenjuju u normalnim terapijskim dozama tokom kratkog vremenskog perioda.
The existence of other professional medical problems might impact the use of this drugs. Make sure you convey to your health practitioner When you've got almost every other clinical difficulties, especially:
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Ova interakcija je od malog značaja kod zdravih osoba, ali nije jasno da li drugi faktori, kao što su starije životno doba ili ciroza jetre, povećavaju rizik od pojave neželjenih dejstava prilikom istovremene upotrebe.
Po prestanku terapije može se javiti prolazni sindrom u okviru koga se vraćaju simptomi koji su bili razlog za primenu benzodiazepina, i to u pojačanoj formi. Oni mogu biti udruženi sa drugim neželjenim reakcijama uključujući promene raspoloženja, anksioznost ili poremećaje spavanja i uznemirenost.
Kod pacijenata sa oslabljenom funkcijom bubrega treba primenjivati opšte mere opreza. Kod pacijenata sa insuficijencijom bubrega poluvreme eliminacije more info diazepama nije klinički značajno promenjeno, pa obično nije check here neophodno prilagođavanje doze kod ovih pacijenata.
It is very important that the health practitioner Examine your or your son or daughter's development at regular visits, In particular within the very first 24 to 72 hours of treatment, to be certain the medication is Operating effectively. Blood and urine exams might be needed to check for any unwelcome effects.
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If anyone has overdosed and it has serious indicators for example passing out or difficulties respiration, give them naloxone if obtainable, then get in touch with 911. If the individual is awake and it has no signs and symptoms, phone a poison Handle Middle at once.
Disclaimer: This information is for informational reasons only and shouldn't be regarded medical advice. Normally talk to with a Health care Specialist before beginning any new medication.
U malom broju slučajeva, prijavljeno je da je istovremena primena sa diazepamom smanjila dejstvo levodope.
Rizik od pojave zavisnosti raste sa porastom doze i trajanja lečenja, i veći je kod pacijenata koji u anamnezi imaju alkoholizam i zloupotrebu lekova ili kod pacijenata sa izraženim poremećajem ličnosti.